Chemical peels have long been used for revealing fresh, glowing skin. In 2025, the evolution of skin peels continues with advanced formulations that address a range of skin concerns, offering minimal downtime, side effects, and maximum results compared to older peels.
Among the most in-demand chemical peels that you should know about are BioRePeel, Cosmelan, Dermamelan, and PRX-T33. But which one is right for you?
In this blog, explore these top peels, their benefits, and how to choose the right one for your skin goals.
What Are Chemical Peels and How Do They Work?
Before learning more about the latest chemical peels, let’s take a step back to understand what chemical peels are and what they do!
Chemical peels are a skin-resurfacing procedure that uses acid-based solutions. When these solutions are applied to the skin, they cause the outermost layers to exfoliate, revealing newer, more even-toned, fresher skin underneath.
Different types of chemical peels are available. Depending on the type and depth of the peel, they can address a wide range of skin concerns. Modern peels, such as BioRePeel and PRX-T33, combine exfoliation with bio-stimulation. This means they encourage skin regeneration from within, without causing noticeable peeling.
Top 4 Skin Peels in 2025
1. BioRePeel: The No-Downtime Glow Peel
This new-age chemical peel is also popularly known as the no-downtime glow peel and is one of the most innovative options available in the market today.
This revolutionary peel contains:
- 35% Trichloroacetic Acid (TCA)
- Lactic acid
- Salicylic acid
- Tartaric acid
- Vitamins B2 and C
- Amino acids
Unlike traditional TCA peels which exfoliate the superficial layers of the skin till the target area is treated completely, BioRePeel improves skin surface, imperfections and accelerates cell turnover.
Benefits of BioRePeel
BioRePeel offers several benefits, including:
- Improves acne and post-acne scars
- Reduces hyperpigmentation and sun spots
- Refines pores and texture
- Brightens dull or tired-looking skin
- Boosts collagen with little to no downtime
What to Expect During and After Treatment
Here’s a general overview of what happens during a BioRePeel session and what you might notice in the days that follow.
The chemical peel session takes around 30–45 minutes. Most people experience some tingling or warmth, and the pain or discomfort is minimal. Since the process is minimally invasive and involves very little peeling or shedding, most people can resume their normal activities immediately.
Typically, 4–6 sessions spaced 1–2 weeks apart are recommended.
The results of a BioRePeel procedure become evident after one or two sessions, and most people observe smaller pores, tighter skin, reduced pigmentation, a brighter complexion, and even-toned, rejuvenated skin.Â
2. Cosmelan: The Gold Standard for Pigmentation
You read that right! Cosmelan is the latest, medical-grade, and advanced depigmentation treatment trusted worldwide in aesthetic medicine. This chemical peel targets areas of pigmentation and works at the cellular level to inhibit future melanin production.
It comprises:
- Azelaic acid
- Kojic acid
- Phytic acid
- Retinoid derivatives
These ingredients suppress melanin production at the source and lighten dark patches.
What does it treat?
It is highly effective for the following conditions:
- Melasma
- Sun damage
- Age spots
- Post-inflammatory pigmentation
- Uneven skin tone
- Pigmentation related to acne
Cosmelan treatment works in two phases: an in-clinic phase, during which the mask is applied for several hours, followed by an at-home maintenance phase.
Benefits of Cosmelan
Cosmelan targets all types of hyperpigmentation. Some of its benefits include:
- Dramatically reduces pigmentation
- Even out skin tone
- Safe for all skin types and tones
- Prevents melanin overproduction
What to Expect During and After Treatment
After a consultation and skin prep, the dermatologist will apply the Cosmelan professional mask at the clinic. This is allowed to remain on the skin for several hours (approximately 8 to 12 hours) before removal at home, as directed. Most people require one in-clinic session followed by guided home care maintenance sessions.
You may experience redness, peeling and flaking for 5 to 7 days. You may also notice shedding and flaking, which is a normal occurrence. Avoid makeup and sun exposure for a few days, or as recommended by your dermatologist.
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Pigmentation will improve, and the skin begins to look lighter and more even.
3. Dermamelan: Medical-Grade Pigment Control
Dermamelan is an advanced chemical peel with a patented formula that contains a higher concentration of active ingredients found in Cosmelan, resulting in an enhanced melanin-inhibiting action.
This chemical peel works similarly to Cosmelan and has two phases– in-clinic and at-home maintenance. However, it is not recommended for sensitive or reactive skin types.
Benefits of Dermamelan
Dermamelan is a medical-strength version of Cosmelan that offers the following benefits:
- Professional depigmenting solution
- Superior results for severe cases
- Long-term reduction of pigmentation
- Treats the root cause and prevents recurrence
What to Expect During and After Treatment
Most people require just one in-clinic session, followed by a 4-month at-home maintenance phase. At the clinic, the dermatologist will evaluate your suitability for the procedure and apply the Dermamelon mask. The mask must be worn for atleast 8 to 12 hours.Â
This is followed by an at-home phase that involves the application of dermatologist-recommended products with depigmentation action and long-term regulation of pigment overproduction.
It involves applying complementary cosmetic products for 4 months, with a continuous depigmenting action and long-term regulation of pigment overproduction.Â
After Dermamelon treatment, you may experience peeling and redness, which typically subside on their own within 7 to 10 days.
You will begin to see an improvement in your skin texture and reduction in spots and areas of pigmentation a few weeks after the procedure. To ensure improvement in results, the at-home maintenance phase is very important.
To know more, book a consultation with our expert dermatologists at Hortman Clinics, one of the top aesthetic clinics in Dubai.
Pigmentation will improve, and the skin begins to look lighter and more even.
4. PRX-T33: The Unicorn Peel for Radiant Skin
PRX-T33 or the unicorn peel is a biorevitalising solution that combines TCA with hydrogen peroxide to stimulate skin renewal without causing peeling (caused by exfoliation of the skin’s outermost layers).
This advanced chemical peel has an innovative composition:
- 33% TCA (Trichloroacetic acid)
- 5% Kojic acid and
- Hydrogen peroxide
Despite a higher TCA concentration than traditional peels, this peel does not cause any side effects. This is because hydrogen peroxide modulates TCA action and prevents shedding of the outermost skin layer.
Benefits of PRX-T33
- Lifts and tightens skin
- Reduces fine lines and sagging
- Improves acne scars and texture
- Brightens skin tone
- Safe all year round
What to Expect During and After Treatment
After the initial consultation with the dermatologist, they will prepare the skin for a PRX-T33 peel treatment.Â
- The target area on the skin is cleaned and dried.
- PRX-T33 is applied to the skin and gently massaged until it is completely absorbed. Around 2 to 5 applications are done during the session.
- The skin is then washed and rinsed with a water-soaked pad.
- A moisturising, nourishing cream is then applied.
- The session lasts around 30 minutes.
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The doctor will prescribe a moisturiser to be applied 2 to 3 times a day at home.
Most people remain comfortable throughout the procedure, although they may experience mild warmth or tingling sensations.
The effectiveness and revitalising power of this peel is superior to others. It also does not cause desquamation or peeling, thanks to the presence of hydrogen peroxide. There is usually no downtime after a PRX-T33 peel treatment.
Most people require 4 to 6 weekly sessions for effective results.
Key Takeaway!
Takeaway!
Chemical peels are effective in correcting various skin concerns. If you are unhappy with pigmentation, wrinkles, or other skin concerns, visit our expert team of dermatologists at Hortman Clinics to determine if you are a suitable candidate for chemical peels.
At Hortman Clinics, one of the top skin care clinics in Dubai, we offer the most advanced chemical peel treatments to help you reach your aesthetic goals. Schedule a consultation now!
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Everything we do is tailored to your needs, this is why we take our time to take care of you and answer all your questions.